Mysore and Calicut are two major gateway cities for Wayanad region for those considering to travel to Wayanad from Chennai.
Chennai to Bangalore Highway
Calicut in Kerala is the nearest railway station located about 75km south west of Sultan Battery in Wayanad. There are many daily trains from Chennai that goes via Calicut. See the railway stations for Wayanad
Also Calicut has an airport with direct flight to Chennai.
Chennai to Wayanad road distance is about 600km.
The road route is : Chennai --350km--> Bangalore--140km-->Mysore--110km--> Wayanad (Sultan Battery). Drive to Bangalore. Take the NICE Road (expressway) and take the Mysore Road exit. You will skip driving through Bangalore city center. Further follow one of the Bangalore to Wayanad routes
Route A : Bangalore to Wayanad via Mysore, Hunsur, Nagarhole NP, Kutta and Mananthavadi
Route B : Bangalore to Wayanad via Mysore, HD Kote, Kabini, Nagarhole and Mananthavadi.
Route C : Bangalore to Wayanad via Mysore, Gundlupet, Sulthan Bathery and Kalpetta.
Route D : Bangalore to Wayanad via Mysore, Gundlupet, Bandipur , Gudalur and Kalpetta.